What is our question?
For pre-retirement New Zealand adults, how would shifting weekly work hours by ten hours affect 28 well-being outcomes one year later? We compare each shift, upward and downward, with the natural course.
Target trial emulation · NZAVS 2020–2023 · Lab report
How work hours affect well-being: a target trial emulation in a national New Zealand cohort
Ballerina X. S. Chong · Chris G. Sibley · Joseph A. BulbuliaPLOS One · 2026
Work hours are associated with differences in well-being. We ask how well-being would change if weekly work hours increased or decreased. We emulate a target trial using data from 24,579 pre-retirement participants in the New Zealand Attitudes and Values Study (NZAVS). We estimate how 28 well-being outcomes would differ under interventions that shift weekly work hours ten hours up or ten hours down, each compared with the natural course: work hours changing as they ordinarily would.
The emulated trial
A target trial emulation organises an observational study around the question and design of a hypothetical randomised trial.
What is our question?
For pre-retirement New Zealand adults, how would shifting weekly work hours by ten hours affect 28 well-being outcomes one year later? We compare each shift, upward and downward, with the natural course.
What is our population?
The work-hours analysis includes 24,579 NZAVS participants of pre-retirement age at baseline (2020/2021). Work hours are measured in 2021/2022 and outcomes in 2022/2023. Censoring adjustment accounts for people leaving the study, aiming to estimate outcomes for the baseline cohort under complete follow-up.
What interventions do we compare?
Increase weekly work hours by ten, compared with the natural course, which allows work hours to change as they ordinarily would.
Decrease weekly work hours by ten, compared with the natural course, which allows work hours to change as they ordinarily would.
Can the data support the comparison?
To estimate the effects of changing work hours, we need evidence about comparable people working at the hours the intervention would produce. Positivity requires that any set of work-hour values given a positive chance by an intervention also has a positive chance among people with each relevant history. Here, history means the characteristics and earlier survey responses used to compare participants. In practice, we also need enough comparable observations to reliably estimate the effects.
The observed work-hour distributions provide better coverage for the ten-hour reduction. Increasing hours by ten more often produces work-hour values that are rare among people with comparable measured histories. Estimating the upward shift therefore requires more extrapolation: using models to predict outcomes where comparable observations are sparse. That reliance calls for greater caution.
The central result
Estimated effects of the ten-hour shifts concentrate in tiredness, measured as fatigue, and a small set of physical-health outcomes. Most point estimates, our best estimates of the average changes, are small under either policy. Moreover, the data provide stronger empirical support for decreasing hours than for increasing hours. The upward shift therefore warrants greater caution. Comparisons between people at the first survey suggest differences across more outcomes and sometimes point in the opposite direction. However, those associations describe differences between people. The adjusted longitudinal estimates use later outcomes to address the specified changes in work hours.
+10 hours · estimated changes
As noted above, increasing weekly work hours by ten raises estimated fatigue by 0.08 standard deviations, a small change relative to the variation in fatigue across people. Estimated nightly sleep falls by roughly 3.4 minutes. Body mass index increases by roughly 0.19 kg/m² and perceived physical health declines by roughly 0.13 points. However, estimates for sleep, body mass index, and perceived physical health warrant greater caution about uncertainty or residual confounding, distortion from common causes of work hours and well-being that remains after adjustment. The estimated increase in perceived support is also small and sensitive to residual confounding.
−10 hours · estimated changes
As noted above, decreasing weekly work hours by ten lowers estimated fatigue by 0.04 standard deviations. Estimated body mass index falls by 0.13 kg/m², while perceived physical health increases by 0.07 points. However, both physical-health estimates remain sensitive to residual confounding.
The estimates
Estimated average effects of increasing or decreasing weekly work hours by ten, each compared with the natural course. Effects are in standard-deviation units, which express each change relative to the variation in that outcome across people. Bonferroni-adjusted intervals control family-wise error at 5% across 28 outcomes under each policy (approximately 99.82% individual intervals). This adjustment accounts for testing several outcomes together. Green marks the fatigue estimate under each policy, which the paper identifies as least vulnerable to unmeasured confounding. Gold marks estimates whose corrected intervals exclude zero but whose E-value bounds are modest. E denotes the E-value for the confidence limit closest to zero. Larger E-values mean that stronger unmeasured confounding would be needed to move that limit to zero. The paper's supplement reports all 28 outcomes.
Inference & robustness
As stated above, we compare each ten-hour shift in weekly work hours with the natural course, allowing work hours to change as they ordinarily would. Censoring adjustment targets both comparisons to the baseline cohort under complete follow-up.
We estimate the work-hour intervention effects with modified treatment policy estimators in the lmtp R package. Machine-learning models adjust for baseline differences and dropout. Adjustment addresses confounding: common causes of work hours and well-being that can distort their apparent relationship. Residual confounding is the distortion that remains after adjustment. Causal interpretation depends on the study's assumptions about confounding, exposure support, comparable treatment versions, and missing data.
Uncertainty about the work-hour effects remains substantial. Many adjusted point estimates are closer to zero than the baseline associations. Moreover, many Bonferroni-adjusted intervals include zero, leaving uncertainty about the direction of those effects.
The work-hours estimates concern ten-hour shifts among pre-retirement adults. People gain and lose hours for different reasons, which may affect how the results apply to a particular workplace change. Moreover, work hours and outcomes are self-reported. Reporting errors may bias the estimates in a direction that depends on their relations with exposure, outcomes, and confounders.
What this means
Changing work hours appears to affect how tired people feel. A ten-hour increase in the working week raises estimated fatigue, while a ten-hour reduction lowers it. Most estimated changes in other aspects of well-being are small. The data provide better coverage of the work hours needed to estimate a reduction. The results describe average effects among pre-retirement adults and depend on the study's assumptions. For discussions about working time, fatigue is the clearest outcome to consider; broader benefits remain uncertain.
Citation
Chong, B. X. S., Sibley, C. G., & Bulbulia, J. A. (2026). How work hours affect well-being: A target trial emulation. PLOS One. doi:10.1371/journal.pone.0350816
Data: the New Zealand Attitudes and Values Study. Estimation: modified treatment policies with the lmtp R package.
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<div class="report-wrap">
<p class="kicker kicker-dash">Target trial emulation · NZAVS 2020–2023 · Lab report</p>
<h1 class="report-title">Work Hours, Fatigue, and <em>Physical Health</em></h1>
<p class="report-subtitle">How work hours affect well-being: a target trial emulation in a national New Zealand cohort</p>
<p class="byline"><span class="names">Ballerina X. S. Chong · Chris G. Sibley · Joseph A. Bulbulia</span><span class="venue">PLOS One · 2026</span></p>
<p class="report-lede">Work hours are associated with differences in well-being. We ask how well-being would change if weekly work hours increased or decreased. We emulate a target trial using data from 24,579 pre-retirement participants in the New Zealand Attitudes and Values Study (NZAVS). We estimate how 28 well-being outcomes would differ under interventions that shift weekly work hours <span class="hl">ten hours up</span> or <span class="hl-gold">ten hours down</span>, each compared with the natural course: work hours changing as they ordinarily would.</p>
<div class="stat-row" style="margin-top:2.5rem">
<div class="stat"><span class="n">24,579</span><span class="lbl">pre-retirement adults, NZAVS</span></div>
<div class="stat"><span class="n">3</span><span class="lbl">annual waves, 2020/2021–2022/2023</span></div>
<div class="stat"><span class="n">28</span><span class="lbl">well-being outcomes</span></div>
<div class="stat"><span class="n">±10</span><span class="lbl">hours per week, the two policies</span></div>
</div>
<section class="report-section">
<p class="kicker kicker-dash">The emulated trial</p>
<p>A target trial emulation organises an observational study around the question and design of a hypothetical randomised trial.</p>
<div class="trial-grid">
<div class="cell">
<p class="chip soft">What is our question?</p>
<p>For pre-retirement New Zealand adults, how would shifting weekly work hours by ten hours affect 28 well-being outcomes one year later? We compare each shift, upward and downward, with the natural course.</p>
</div>
<div class="cell">
<p class="chip soft">What is our population?</p>
<p>The work-hours analysis includes 24,579 NZAVS participants of pre-retirement age at baseline (2020/2021). Work hours are measured in 2021/2022 and outcomes in 2022/2023. Censoring adjustment accounts for people leaving the study, aiming to estimate outcomes for the baseline cohort under complete follow-up.</p>
</div>
<div class="cell">
<p class="chip soft">What interventions do we compare?</p>
<div class="arm">
<span class="chip">Shift up · +10 hours</span>
<p>Increase weekly work hours by ten, compared with the natural course, which allows work hours to change as they ordinarily would.</p>
</div>
<div class="arm">
<span class="chip gold">Shift down · −10 hours</span>
<p>Decrease weekly work hours by ten, compared with the natural course, which allows work hours to change as they ordinarily would.</p>
</div>
</div>
</div>
</section>
<section class="report-section">
<p class="kicker kicker-dash">Can the data support the comparison?</p>
<h2>Some changes in hours are easier to study</h2>
<p>To estimate the effects of changing work hours, we need evidence about comparable people working at the hours the intervention would produce. Positivity requires that any set of work-hour values given a positive chance by an intervention also has a positive chance among people with each relevant history. Here, history means the characteristics and earlier survey responses used to compare participants. In practice, we also need enough comparable observations to reliably estimate the effects.</p>
<p>The observed work-hour distributions provide better coverage for the ten-hour reduction. Increasing hours by ten more often produces work-hour values that are rare among people with comparable measured histories. Estimating the upward shift therefore requires more extrapolation: using models to predict outcomes where comparable observations are sparse. That reliance calls for greater caution.</p>
</section>
<section class="report-section">
<p class="kicker kicker-dash">The central result</p>
<h2 class="claim" style="margin-top:1rem">Increasing work hours raises estimated fatigue; decreasing hours lowers it.</h2>
<p>Estimated effects of the ten-hour shifts concentrate in tiredness, measured as fatigue, and a small set of physical-health outcomes. Most point estimates, our best estimates of the average changes, are small under either policy. Moreover, the data provide stronger empirical support for decreasing hours than for increasing hours. The upward shift therefore warrants greater caution. Comparisons between people at the first survey suggest differences across more outcomes and sometimes point in the opposite direction. However, those associations describe differences between people. The adjusted longitudinal estimates use later outcomes to address the specified changes in work hours.</p>
<div class="duo">
<div class="panel">
<p class="chip">+10 hours · estimated changes</p>
<h3>Higher fatigue and less sleep</h3>
<p>As noted above, increasing weekly work hours by ten raises estimated fatigue by 0.08 standard deviations, a small change relative to the variation in fatigue across people. Estimated nightly sleep falls by roughly 3.4 minutes. Body mass index increases by roughly 0.19 kg/m² and perceived physical health declines by roughly 0.13 points. However, estimates for sleep, body mass index, and perceived physical health warrant greater caution about uncertainty or residual confounding, distortion from common causes of work hours and well-being that remains after adjustment. The estimated increase in perceived support is also small and sensitive to residual confounding.</p>
</div>
<div class="panel">
<p class="chip gold">−10 hours · estimated changes</p>
<h3>Lower fatigue</h3>
<p>As noted above, decreasing weekly work hours by ten lowers estimated fatigue by 0.04 standard deviations. Estimated body mass index falls by 0.13 kg/m², while perceived physical health increases by 0.07 points. However, both physical-health estimates remain sensitive to residual confounding.</p>
</div>
</div>
</section>
<section class="report-section">
<p class="kicker kicker-dash">The estimates</p>
<div class="figure-panel">
<svg viewBox="0 0 780 372" xmlns="http://www.w3.org/2000/svg" role="img" font-family="JetBrains Mono, ui-monospace, Menlo, monospace">
<circle cx="6" cy="16" r="4.5" fill="var(--green)"/>
<text x="17" y="20" font-size="10.5" fill="var(--ink-soft)">least vulnerable to unmeasured confounding</text>
<circle cx="6" cy="36" r="4.5" fill="var(--gold)"/>
<text x="17" y="40" font-size="10.5" fill="var(--ink-soft)">interval excludes zero; E-value bound modest</text>
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<text x="316.8" y="354" font-size="10" fill="var(--ink-faint)" text-anchor="middle">-0.10</text>
<text x="382.8" y="354" font-size="10" fill="var(--ink-faint)" text-anchor="middle">-0.05</text>
<text x="448.8" y="354" font-size="10" fill="var(--ink-faint)" text-anchor="middle">0</text>
<text x="514.8" y="354" font-size="10" fill="var(--ink-faint)" text-anchor="middle">+0.05</text>
<text x="580.8" y="354" font-size="10" fill="var(--ink-faint)" text-anchor="middle">+0.10</text>
<text x="0" y="96.0" font-size="11" font-weight="700" letter-spacing="1.5" fill="var(--ink)">+10 HOURS PER WEEK</text>
<g>
<title>fatigue: 0.079 [0.035, 0.123], E-value bound 1.22</title>
<text x="250" y="127.5" font-size="10.5" letter-spacing="1" fill="var(--ink-soft)" text-anchor="end">FATIGUE</text>
<line x1="495.0" y1="124.0" x2="611.2" y2="124.0" stroke="var(--green)" stroke-width="2" stroke-linecap="round"/>
<circle cx="553.1" cy="124.0" r="4.5" fill="var(--green)" stroke="var(--card)" stroke-width="2"/>
<text x="780" y="127.5" font-size="10" fill="var(--ink-faint)" text-anchor="end">+0.079 · E 1.22</text>
</g>
<g>
<title>perceived physical health: -0.055 [-0.100, -0.010], E-value bound 1.10</title>
<text x="250" y="159.5" font-size="10.5" letter-spacing="1" fill="var(--ink-soft)" text-anchor="end">PERCEIVED PHYSICAL HEALTH</text>
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<text x="780" y="159.5" font-size="10" fill="var(--ink-faint)" text-anchor="end">-0.055 · E 1.10</text>
</g>
<g>
<title>perceived support: 0.047 [0.002, 0.092], E-value bound 1.04</title>
<text x="250" y="191.5" font-size="10.5" letter-spacing="1" fill="var(--ink-soft)" text-anchor="end">PERCEIVED SUPPORT</text>
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<circle cx="510.8" cy="188.0" r="4.5" fill="var(--gold)" stroke="var(--card)" stroke-width="2"/>
<text x="780" y="191.5" font-size="10" fill="var(--ink-faint)" text-anchor="end">+0.047 · E 1.04</text>
</g>
<text x="0" y="224.0" font-size="11" font-weight="700" letter-spacing="1.5" fill="var(--ink)">−10 HOURS PER WEEK</text>
<g>
<title>fatigue: -0.042 [-0.069, -0.015], E-value bound 1.13</title>
<text x="250" y="255.5" font-size="10.5" letter-spacing="1" fill="var(--ink-soft)" text-anchor="end">FATIGUE</text>
<line x1="357.7" y1="252.0" x2="429.0" y2="252.0" stroke="var(--green)" stroke-width="2" stroke-linecap="round"/>
<circle cx="393.4" cy="252.0" r="4.5" fill="var(--green)" stroke="var(--card)" stroke-width="2"/>
<text x="780" y="255.5" font-size="10" fill="var(--ink-faint)" text-anchor="end">-0.042 · E 1.13</text>
</g>
<g>
<title>body mass index: -0.020 [-0.034, -0.006], E-value bound 1.08</title>
<text x="250" y="287.5" font-size="10.5" letter-spacing="1" fill="var(--ink-soft)" text-anchor="end">BODY MASS INDEX</text>
<line x1="403.9" y1="284.0" x2="440.9" y2="284.0" stroke="var(--gold)" stroke-width="2" stroke-linecap="round"/>
<circle cx="422.4" cy="284.0" r="4.5" fill="var(--gold)" stroke="var(--card)" stroke-width="2"/>
<text x="780" y="287.5" font-size="10" fill="var(--ink-faint)" text-anchor="end">-0.020 · E 1.08</text>
</g>
<g>
<title>perceived physical health: 0.030 [0.003, 0.057], E-value bound 1.06</title>
<text x="250" y="319.5" font-size="10.5" letter-spacing="1" fill="var(--ink-soft)" text-anchor="end">PERCEIVED PHYSICAL HEALTH</text>
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<text x="780" y="319.5" font-size="10" fill="var(--ink-faint)" text-anchor="end">+0.030 · E 1.06</text>
</g>
</svg>
</div>
<p class="fig-caption">Estimated average effects of increasing or decreasing weekly work hours by ten, each compared with the natural course. Effects are in standard-deviation units, which express each change relative to the variation in that outcome across people. Bonferroni-adjusted intervals control family-wise error at 5% across 28 outcomes under each policy (approximately 99.82% individual intervals). This adjustment accounts for testing several outcomes together. Green marks the fatigue estimate under each policy, which the paper identifies as least vulnerable to unmeasured confounding. Gold marks estimates whose corrected intervals exclude zero but whose E-value bounds are modest. E denotes the E-value for the confidence limit closest to zero. Larger E-values mean that stronger unmeasured confounding would be needed to move that limit to zero. The paper's supplement reports all 28 outcomes.</p>
</section>
<section class="report-section">
<p class="kicker kicker-dash">Inference & robustness</p>
<div class="numbered">
<div class="item">
<span class="num">01</span><h3>The natural course comparator</h3>
<p>As stated above, we compare each ten-hour shift in weekly work hours with the natural course, allowing work hours to change as they ordinarily would. Censoring adjustment targets both comparisons to the baseline cohort under complete follow-up.</p>
</div>
<div class="item">
<span class="num">02</span><h3>Adjustment</h3>
<p>We estimate the work-hour intervention effects with modified treatment policy estimators in the <code>lmtp</code> R package. Machine-learning models adjust for baseline differences and dropout. Adjustment addresses confounding: common causes of work hours and well-being that can distort their apparent relationship. Residual confounding is the distortion that remains after adjustment. Causal interpretation depends on the study's assumptions about confounding, exposure support, comparable treatment versions, and missing data.</p>
</div>
<div class="item">
<span class="num">03</span><h3>Uncertainty</h3>
<p>Uncertainty about the work-hour effects remains substantial. Many adjusted point estimates are closer to zero than the baseline associations. Moreover, many Bonferroni-adjusted intervals include zero, leaving uncertainty about the direction of those effects.</p>
</div>
<div class="item">
<span class="num">04</span><h3>Scope</h3>
<p>The work-hours estimates concern ten-hour shifts among pre-retirement adults. People gain and lose hours for different reasons, which may affect how the results apply to a particular workplace change. Moreover, work hours and outcomes are self-reported. Reporting errors may bias the estimates in a direction that depends on their relations with exposure, outcomes, and confounders.</p>
</div>
</div>
</section>
<section class="report-section">
<p class="kicker kicker-dash">What this means</p>
<p>Changing work hours appears to affect how tired people feel. A ten-hour increase in the working week raises estimated fatigue, while a ten-hour reduction lowers it. Most estimated changes in other aspects of well-being are small. The data provide better coverage of the work hours needed to estimate a reduction. The results describe average effects among pre-retirement adults and depend on the study's assumptions. For discussions about working time, fatigue is the clearest outcome to consider; broader benefits remain uncertain.</p>
</section>
<div class="report-note">
<p class="kicker">Citation</p>
<p>Chong, B. X. S., Sibley, C. G., & Bulbulia, J. A. (2026). How work hours affect well-being: A target trial emulation. <i>PLOS One</i>. <a href="https://doi.org/10.1371/journal.pone.0350816">doi:10.1371/journal.pone.0350816</a></p>
<p>Data: the New Zealand Attitudes and Values Study. Estimation: modified treatment policies with the <code>lmtp</code> R package.</p>
</div>
</div>
```